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Fatigue-resistant hydrogel optical fibers enable peripheral nerve optogenetics during locomotion
We develop soft and stretchable fatigue-resistant hydrogel optical fibers that enable optogenetic modulation of peripheral nerves in …
Xinyue Liu
,
Siyuan Rao
,
Weixuan Chen
,
Kayla Felix"
,
Jiahua Ni
,
Atharva Sahasrabudhe
,
Shaoting Lin
,
Qianbin Wang
,
Yuanyuan Liu
,
Zhigang He
,
Jingyi Xu
,
Eunji Hong
,
Todd Yau
,
Polina Anikeeva
,
Xuanhe Zhao
Cite
DOI
Multifunctional fibers enable modulation of cortical and deep brain activity during cognitive behavior in macaques
Recording and modulating neural activity in vivo enables investigations of the neurophysiology underlying behavior and disease. …
Indie Garwood
,
Alex J Major
,
Marc-Joseph Antonini
,
Josefina Correa
,
Youngbin Lee
,
Atharva Sahasrabudhe
,
Meredith K Mahnke
,
Earl K Miller
,
Emery N Brown
,
Polina Anikeeva
PDF
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DOI
Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits
Progress in understanding brain–viscera interoceptive signaling is hindered by a dearth of implantable devices suitable for probing …
Atharva Sahasrabudhe
,
Laura E. Rupprecht
,
Sirma Orguc
,
Tural Khudiyev
,
Tomo Tanaka
,
Joanna Sands
,
Weikun Zhu
,
Anthony Tabet
,
Marie Manthey
,
Harrison Allen
,
Gabriel Loke
,
Marc-Joseph Antonini
,
Dekel Rosenfeld
,
Jimin Park
,
Indie C. Garwood
,
Wei Yan
,
Farnaz Niroui
,
Yoel Fink
,
Anantha Chandrakasan
,
Diego V. Bohórquez
,
Polina Anikeeva
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DOI
Magnetically Actuated Fiber‐Based Soft Robots
Abstract Broad adoption of magnetic soft robotics is hampered by the sophisticated field paradigms for their manipulation and the …
Youngbin Lee
,
Florian Koehler
,
Tom Dillon
,
Gabriel Loke
,
Yoonho Kim
,
Juliette Marion
,
Marc‐Joseph Antonini
,
Indie Garwood
,
Atharva Sahasrabudhe
,
Keisuke Nagao
,
Xuanhe Zhao
,
Yoel Fink
,
Ellen T. Roche
,
Polina Anikeeva
PDF
Cite
DOI
Modulating cell signalling in vivo with magnetic nanotransducers
Weak magnetic fields offer nearly lossless transmission of signals within biological tissue. Magnetic nanomaterials are capable of …
Gabriela Romero
,
Jimin Park
,
Florian Koehler
,
Arnd Pralle
,
Polina Anikeeva
Cite
DOI
Generalized design principles for hydrodynamic electron transport in anisotropic metals
Interactions of charge carriers with lattice vibrations, or phonons, play a critical role in unconventional electronic transport of …
Yaxian Wang
,
Georgios Varnavides
,
Ravishankar Sundararaman
,
Polina Anikeeva
,
Johannes Gooth
,
Claudia Felser
,
Prineha Narang
Cite
DOI
Magnetothermal Modulation of Calcium‐Dependent Nerve Growth
Nerve injuries are common, and the available treatments including invasive surgeries do not guarantee complete regeneration of the …
Dekel Rosenfeld
,
Hannah Field
,
Ye Ji Kim
,
Karen Ka Lam Pang
,
Keisuke Nagao
,
Florian Koehler
,
Polina Anikeeva
PDF
Cite
DOI
Reprogramming brain immunosurveillance with engineered cytokines
Immune surveillance of the brain is regulated by resident non-neuronal cells and the blood-brain barrier. 1 Dys-regulation of …
Anthony Tabet
,
Yash Agarwal
,
Jordan Stinson
,
Caroline Apra
,
Veronica Will
,
Marie Manthey
,
Noor Momin
,
Allison Sheen
,
Mitchell Murdock
,
Luciano Santollani
,
Li-Huei Tsai
,
Isaac Chiu
,
Sean Lawler
,
Darrell J. Irvine
,
K. Dane Wittrup
,
Polina Anikeeva
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DOI
Probing Neuro-Endocrine Interactions Through Remote Magnetothermal Adrenal Stimulation
to stressful or traumatic stimuli may alter hypothalamic-pituitary-adrenal (HPA) axis and sympathoadrenal-medullary (SAM) reactivity. …
Lisa Y. Maeng
,
Dekel Rosenfeld
,
Gregory J. Simandl
,
Florian Koehler
,
Alexander W. Senko
,
Junsang Moon
,
Georgios Varnavides
,
Maria F. Murillo
,
Adriano E. Reimer
,
Aaron Wald
,
Polina Anikeeva
,
Alik S. Widge
Cite
DOI
Building a culture of responsible neurotech: Neuroethics as socio-technical challenges
Scientists around the globe are joining the race to achieve engineering feats to read, write, modulate, and interface with the human …
Jacob T. Robinson
,
Karen S. Rommelfanger
,
Polina Anikeeva
,
Arnelle Etienne
,
Jennifer French
,
Jennifer Gelinas
,
Pulkit Grover
,
Rosalind Picard
Cite
DOI
Changes in Brain Neuroimmunology Following Injury and Disease
nervous and immune systems are intimately related in the brain and in the periphery, where changes to one affect the other and …
Anthony Tabet
,
Caroline Apra
,
Alexis M. Stranahan
,
Polina Anikeeva
Cite
DOI
Probing carrier interactions using electron hydrodynamics
Electron hydrodynamics arises when momentum-relaxing scattering processes are slow compared to momentum-conserving ones. While the …
Georgios Varnavides
,
Adam S Jermyn
,
Polina Anikeeva
,
Prineha Narang
Cite
DOI
Mesoscopic finite-size effects of unconventional electron transport in PdCoO2
A wide range of unconventional transport phenomena has recently been observed in single-crystal delafossite metals. Here, we present a …
Georgios Varnavides
,
Yaxian Wang
,
Philip J. W. Moll
,
Polina Anikeeva
,
Prineha Narang
Cite
DOI
Thermally Drawn Highly Conductive Fibers with Controlled Elasticity
Electronic fabrics necessitate both electrical conductivity and, like any textile, elastic recovery. Achieving both requirements on the …
Juliette S. Marion
,
Nikhil Gupta
,
Henry Cheung
,
Kirmina Monir
,
Polina Anikeeva
,
Yoel Fink
Cite
DOI
The preference for sugar over sweetener depends on a gut sensor cell
Guided by gut sensory cues, humans and animals prefer nutritive sugars over non-caloric sweeteners, but how the gut steers such …
Kelly L. Buchanan
,
Laura E. Rupprecht
,
M. Maya Kaelberer
,
Atharva Sahasrabudhe
,
Marguerita E. Klein
,
Jorge A. Villalobos
,
Winston W. Liu
,
Annabelle Yang
,
Justin Gelman
,
Seongjun Park
,
Polina Anikeeva
,
Diego V. Bohórquez
Cite
DOI
Magnetothermal nanoparticle technology alleviates parkinsonian-like symptoms in mice
Deep brain stimulation (DBS) has long been used to alleviate symptoms in patients suffering from psychiatric and neurological disorders …
Sarah-Anna Hescham
,
Po-Han Chiang
,
Danijela Gregurec
,
Junsang Moon
,
Michael G. Christiansen
,
Ali Jahanshahi
,
Huajie Liu
,
Dekel Rosenfeld
,
Arnd Pralle
,
Polina Anikeeva
,
Yasin Temel
Cite
DOI
Imaging phonon-mediated hydrodynamic flow in WTe2
In the presence of interactions, electrons in condensed-matter systems can behave hydrodynamically, exhibiting phenomena associated …
Uri Vool
,
Assaf Hamo
,
Georgios Varnavides
,
Yaxian Wang
,
Tony X Zhou
,
Nitesh Kumar
,
Yuliya Dovzhenko
,
Ziwei Qiu
,
Christina A Garcia
,
Andrew T Pierce
,
Johannes Gooth
,
Polina Anikeeva
,
Claudia Felser
,
Prineha Narang
,
Amir Yacoby
PDF
Cite
DOI
Capturing 3D atomic defects and phonon localization at the 2D heterostructure interface
The three-dimensional (3D) local atomic structures and crystal defects at the interfaces of heterostructures control their electronic, …
Xuezeng Tian
,
Xingxu Yan
,
Georgios Varnavides
,
Yakun Yuan
,
Dennis S. Kim
,
Christopher J. Ciccarino
,
Polina Anikeeva
,
Ming-Yang Li
,
Lain-Jong Li
,
Prineha Narang
,
Xiaoqing Pan
,
Jianwei Miao
PDF
Cite
DOI
Generalized Design Principles for Hydrodynamic Electron Transport in Anisotropic Materials
Interactions of charge carriers with lattice vibrations, or phonons, play a critical role in unconventional electronic transport of …
Yaxian Wang
,
Georgios Varnavides
,
Polina Anikeeva
,
Johannes Gooth
,
Claudia Felser
,
Prineha Narang
PDF
Cite
DOI
Modular Integration of Hydrogel Neural Interfaces
Thermal drawing has been recently leveraged to yield multifunctional, fiber-based neural probes at near kilometer length scales. …
Anthony Tabet
,
Marc-Joseph Antonini
,
Atharva Sahasrabudhe
,
Jimin Park
,
Florian Koehler
,
Dekel Rosenfeld
,
Hyunwoo Yuk
,
Samuel Hanson
,
Jordan Stinson
,
Melissa Stok
,
Xuanhe Zhao
,
Chun Wang
,
Polina Anikeeva
Cite
DOI
Electrochemical Modulation of Carbon Monoxide-Mediated Cell Signaling
Despite the critical role played by carbon monoxide (CO) in physiological and pathological signaling events, current approaches to …
Jimin Park
,
Joy S Zeng
,
Atharva Sahasrabudhe
,
Kyoungsuk Jin
,
Yoel Fink
,
Karthish Manthiram
,
Polina Anikeeva
PDF
Cite
DOI
Influence of Magnetic Fields on Electrochemical Reactions of Redox Cofactor Solutions
Redox cofactors mediate many enzymatic processes and are increasingly employed in biomedical and energy applications. Exploring the …
Jimin Park
,
Florian Koehler
,
Georgios Varnavides
,
Marc-Joseph Antonini
,
Polina Anikeeva
PDF
Cite
DOI
Finite-size effects of electron transport in PdCoO2
A wide range of unconventional transport phenomena have recently been observed in single-crystal delafossite metals. Here, we present a …
Georgios Varnavides
,
Yaxian Wang
,
Philip J.W. Moll
,
Polina Anikeeva
,
Prineha Narang
PDF
Cite
DOI
Customizing Multifunctional Neural Interfaces through Thermal Drawing Process
Fiber drawing enables scalable fabrication of multifunctional flexible fibers that integrate electrical, optical and microfluidic …
Marc-Joseph Antonini
,
Atharva Sahasrabudhe
,
Anthony Tabet
,
Miriam Schwalm
,
Dekel Rosenfeld
,
Indie Garwood
,
Jimin Park
,
Gabriel Loke
,
Tural Khudiyev
,
Mehmet Kanik
,
Nathan Corbin
,
Andres Canales
,
Alan Jasanoff
,
Yoel Fink
,
Polina Anikeeva
PDF
Cite
DOI
Modular Integration of Hydrogel Neural Interfaces
Thermal drawing has been recently leveraged to yield multi-functional, fiber-based neural probes at near kilometer length scales. …
Anthony Tabet
,
Marc-Joseph Antonini
,
Atharva Sahasrabudhe
,
Jimin Park
,
Dekel Rosenfeld
,
Florian Koehler
,
Hyunwoo Yuk
,
Samuel Hanson
,
Jordan A. Stinson
,
Melissa Stok
,
Xuanhe Zhao
,
Chun Wang
,
Polina Anikeeva
PDF
Cite
DOI
Fiber-Based Electrochemical Biosensors for Monitoring pH and Transient Neurometabolic Lactate
Developing tools that are able to monitor transient neurochemical dynamics is important to decipher brain chemistry and function. …
Marsilea A. Booth
,
Sally A. N. Gowers
,
Melinda Hersey
,
Isabelle C. Samper
,
Seongjun Park
,
Polina Anikeeva
,
Parastoo Hashemi
,
Molly M. Stevens
,
Martyn G. Boutelle
PDF
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DOI
Direct Imaging and Electronic Structure Modulation of moiré Superlattices at the 2D/3D Interface
The atomic structure at the interface between two-dimensional (2D) and three-dimensional (3D) materials influences properties such as …
Kate Reidy
,
Georgios Varnavides
,
Joachim Dahl Thomsen
,
Abinash Kumar
,
Thang Pham
,
Arthur M Blackburn
,
Polina Anikeeva
,
Prineha Narang
,
James M LeBeau
,
Frances M Ross
PDF
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DOI
Functional Skeletal Muscle Regeneration with Thermally Drawn Porous Fibers and Reprogrammed Muscle Progenitors for Volumetric Muscle Injury
Skeletal muscle has an inherent capacity for spontaneous regeneration. However, recovery after severe injuries such as volumetric …
Yoonhee Jin
,
Dena Shahriari
,
Eun Je Jeon
,
Seongjun Park
,
Yi Sun Choi
,
Jonghyeok Back
,
Hyungsuk Lee
,
Polina Anikeeva
,
Seung-Woo Cho
PDF
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DOI
Selectively Micro-Patternable Fibers via In-Fiber Photolithography
Multimaterial fibers engineered to integrate glasses, metals, semiconductors, and composites found applications in ubiquitous sensing, …
Youngbin Lee
,
Andres Canales
,
Gabriel Loke
,
Mehmet Kanik
,
Yoel Fink
,
Polina Anikeeva
PDF
Cite
DOI
Emerging Frontier of Peripheral Nerve and Organ Interfaces
The development of new tools to interface with the nervous system, empowered by advances in electronics and materials science, has …
Dena Shahriari
,
Dekel Rosenfeld
,
Polina Anikeeva
PDF
Cite
DOI
In vivo photopharmacology enabled by multifunctional fibers
Photoswitchable ligands can add an optical switch to a target receptor or signaling cascade and enable reversible control of neural …
James A Frank
,
Marc-Joseph Antonini
,
Pohan Chiang
,
Andres Canales
,
David Konrad
,
Indie Garwood
,
Gabriela Rajic
,
Florian Koehler
,
Yoel Fink
,
Polina Anikeeva
PDF
Cite
DOI
Electron hydrodynamics in anisotropic materials
Rotational invariance strongly constrains the viscosity tensor of classical fluids. When this symmetry is broken in anisotropic …
Georgios Varnavides
,
Adam S Jermyn
,
Polina Anikeeva
,
Claudia Felser
,
Prineha Narang
PDF
Cite
DOI
Remotely controlled proton generation for neuromodulation
Understanding and modulating proton-mediated biochemical processes in living organisms have been impeded by the lack of tools to …
Jimin Park
,
Anthony Tabet
,
Junsang Moon
,
Pohan Chiang
,
Florian Koehler
,
Atharva Sahasrabudhe
,
Polina Anikeeva
Cite
DOI
Magnetothermal Multiplexing for Selective Remote Control of Cell Signaling
Magnetic nanoparticles have garnered sustained research interest for their promise in biomedical applications including diagnostic …
Junsang Moon
,
Michael G Christiansen
,
Siyuan Rao
,
Colin Marcus
,
David C Bono
,
Dekel Rosenfeld
,
Danijela Gregurec
,
Georgios Varnavides
,
Pohan Chiang
,
Seongjun Park
,
Polina Anikeeva
Cite
DOI
In situ electrochemical generation of nitric oxide for neuronal modulation
Understanding the function of nitric oxide, a lipophilic messenger in physiological processes across nervous, cardiovascular and immune …
Jimin Park
,
Kyoungsuk Jin
,
Atharva Sahasrabudhe
,
Pohan Chiang
,
Joseph H. Maalouf
,
Florian Koehler
,
Dekel Rosenfeld
,
Siyuan Rao
,
Tomo Tanaka
,
Tural Khudiyev
,
Zachary J. Schifer
,
Yoel Fink
,
Ofer Yizhar
,
Karthish Manthiram
,
Polina Anikeeva
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DOI
Applying support-vector machine learning algorithms toward predicting host-guest interactions with cucurbit[7]uril
Machine learning is a valuable tool in the development of chemical technologies but its applications into supramolecular chemistry have …
Anthony Tabet
,
Thomas Gebhart
,
Guanglu Wu
,
Charlie Readman
,
Merrick Pierson Smela
,
Vijay K Rana
,
Cole Baker
,
Harry Bulstrode
,
Polina Anikeeva
,
David H Rowitch
,
Oren A Scherman
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DOI
Magnetic Vortex Nanodiscs Enable Remote Magnetomechanical Neural Stimulation
Magnetic nanomaterials in magnetic fields can serve as versatile transducers for remote interrogation of cell functions. In this study, …
Danijela Gregurec
,
Alexander W Senko
,
Andrey Chuvilin
,
Pooja Reddy
,
Ashwin Sankararaman
,
Dekel Rosenfeld
,
Pohan Chiang
,
Francisco Garcia
,
Ian Tafel
,
Georgios Varnavides
,
Eugenia Ciocan
,
Polina Anikeeva
Cite
DOI
Functionally Distinct Neuronal Ensembles within the Memory Engram
Memories are believed to be encoded by sparse ensembles of neurons in the brain. However, it remains unclear whether there is …
Xiaochen Sun
,
Max J Bernstein
,
Meizhen Meng
,
Siyuan Rao
,
Andreas T Sørensen
,
Li Yao
,
Xiaohui Zhang
,
Polina O Anikeeva
,
Yingxi Lin
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DOI
Transgene-free remote magnetothermal regulation of adrenal hormones
The field of bioelectronic medicines seeks to modulate electrical signaling within peripheral organs, providing temporally precise …
Dekel Rosenfeld
,
Alexander W Senko
,
Junsang Moon
,
Isabel Yick
,
Georgios Varnavides
,
Danijela Gregurec
,
Florian Koehler
,
Pohan Chiang
,
Michael G Christiansen
,
Lisa Y Maeng
,
Alik S Widge
,
Polina Anikeeva
Cite
DOI
A gut sensor for sugar preference
Animals innately prefer caloric sugars over non-caloric sweeteners. Such preference depends on the sugar entering the intestine.1–4 …
Kelly L Buchanan
,
Laura E Rupprecht
,
Atharva Sahasrabudhe
,
Melanie Maya Kaelberer
,
Marguerita E Klein
,
Jorge Villalobos
,
Winston W Liu
,
Annabelle Yang
,
Justin Gelman
,
Seongjun Park
,
Polina Anikeeva
,
Diego V Bohorquez
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DOI
Polymer-fiber-coupled field-effect sensors for label-free deep brain recordings
Electrical recording permits direct readout of neural activity but offers limited ability to correlate it to the network topography. On …
Yuanyuan Guo
,
Carl F Werner
,
Andres Canales
,
Li Yu
,
Xiaoting Jia
,
Polina Anikeeva
,
Tatsuo Yoshinobu
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DOI
Voices in methods development
To mark the 15th anniversary of Nature Methods, we asked scientists from across diverse fields of basic biology research for their …
Polina Anikeeva
,
Edward Boyden
,
Clifford Brangwynne
,
Ibrahim I Cissé
,
Oliver Fiehn
,
Petra Fromme
,
Anne Claude Gingras
,
Casey S Greene
,
Edith Heard
,
Stefan W Hell
,
Elizabeth Hillman
,
Grant Jay Jensen
,
Rachel Karchin
,
Laura L Kiessling
,
Benjamin P Kleinstiver
,
Rob Knight
,
Philipp Kukura
,
Madeline A Lancaster
,
Nicholas Loman
,
Loren Looger
,
Emma Lundberg
,
Qingming Luo
,
Atsushi Miyawaki
,
Eugene W Myers Jr
,
Garry P Nolan
,
Paola Picotti
,
Wolf Reik
,
Markus Saurer
,
Alex K Shalek
,
Jay Shendure
,
Nikolai Slavov
,
Amos Tanay
,
Olga Troyanskaya
,
David van Valen
,
Hong-Wei Wang
,
Chengqi Yi
,
Peng Yin
,
Magdalena Zernicka-Goetz
,
Xiaowei Zhuang
Cite
DOI
Nonequilibrium phonon transport across nanoscale interfaces
Despite the ubiquity of applications of heat transport across nanoscale interfaces, including integrated circuits, thermoelectrics, and …
Georgios Varnavides
,
Adam S Jermyn
,
Polina Anikeeva
,
Prineha Narang
Cite
DOI
Remotely controlled chemomagnetic modulation of targeted neural circuits
Connecting neural circuit output to behaviour can be facilitated by the precise chemical manipulation of specific cell populations. …
Siyuan Rao
,
Ritchie Chen
,
Ava A LaRocca
,
Michael G Christiansen
,
Alexander W Senko
,
Cindy H Shi
,
Pohan Chiang
,
Georgios Varnavides
,
Jian Xue
,
Yang Zhou
,
Seongjun Park
,
Ruihua Ding
,
Junsang Moon
,
Guoping Feng
,
Polina Anikeeva
Cite
DOI
Next-generation interfaces for studying neural function
Monitoring and modulating the diversity of signals used by neurons and glia in a closed-loop fashion is necessary to establish …
James A Frank
,
Marc-Joseph Antonini
,
Polina Anikeeva
Cite
DOI
Strain-programmable fiber-based artificial muscle
Artificial muscles may accelerate the development of robotics, haptics, and prosthetics. Although advances in polymer-based actuators …
Mehmet Kanik
,
Sirma Orguc
,
Georgios Varnavides
,
Jinwoo Kim
,
Thomas Benavides
,
Dani Gonzalez
,
Timothy Akintilo
,
C Cem Tasan
,
Anantha P Chandrakasan
,
Yoel Fink
,
Polina Anikeeva
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DOI
Scalable Fabrication of Porous Microchannel Nerve Guidance Scaffolds with Complex Geometries
Microchannel scaffolds accelerate nerve repair by guiding growing neuronal processes across injury sites. Although geometry, materials …
Dena Shahriari
,
Gabriel Loke
,
Ian Tafel
,
Seongjun Park
,
Pohan Chiang
,
Yoel Fink
,
Polina Anikeeva
PDF
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DOI
Progress in neuromodulation of the brain; a role for magnetic nanoparticles?
The field of neuromodulation is developing rapidly. Current techniques, however, are still limited as they i) either depend on …
Milaine Roet
,
Sarah-Anna Hescham
,
Ali Jahanshahi
,
Bart PF Rutten
,
Polina Anikeeva
,
Yasin Temel
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DOI
Flexible fiber-based optoelectronics for neural interfaces
Neurological and psychiatric conditions pose an increasing socioeconomic burden on our aging society. Our ability to understand and …
Seongjun Park
,
Gabriel Loke
,
Yoel Fink
,
Polina Anikeeva
Cite
DOI
Optogenetic surface stimulation of the rat cervical spinal cord
Electrical intraspinal microstimulation (ISMS) at various sites along the cervical spinal cord permits forelimb muscle activation, …
Sarah E Mondello
,
Michael D Sunshine
,
Amanda E Fischedick
,
Sam J Dreyer
,
Gregory D Horwitz
,
Polina Anikeeva
,
Philip J Horner
,
Chet T Moritz
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DOI
Optogenetic entrainment of neural oscillations with hybrid fiber probes
Objective. Optogenetic modulation of neural activity is a ubiquitous tool for basic investigation of brain circuits. While the majority …
Antje Kilias
,
Andres Canales
,
Ulrich P Froriep
,
Seongjun Park
,
Ulrich Egert
,
Polina Anikeeva
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DOI
Silicon biointerfaces for all scales
Design principles for the development of silicon biointerfaces enable the non-genetic, light-controlled modulation of intracellular …
Seongjun Park
,
James A Frank
,
Polina Anikeeva
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DOI
Creating Functional Interfaces with Biological Circuits
Polina Anikeeva
,
Charles M Lieber
,
Jinwoo Cheon
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DOI
Editorial overview: Neurotechnologies.
In this issue of CONB we highlight recent developments in tools to interrogate neuronal function across species ranging from fruit …
Polina Anikeeva
,
Liqun Luo
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DOI
Visions for the Future of Neuroscience
Neuroscience is a broad discipline that embraces technology at multiple scales to understand the brain and to develop potential …
Tirin Moore
,
Cynthia Chestek
,
Daniel Polley
,
Alon Chen
,
Simon Hippenmeyer
,
Polina Anikeeva
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DOI
Multifunctional fibers as tools for neuroscience and neuroengineering
Multifunctional devices for modulation and probing of neuronal activity during free behavior facilitate studies of functions and …
Andres Canales
,
Seongjun Park
,
Antje Kilias
,
Polina Anikeeva
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DOI
Roadmap on semiconductor--cell biointerfaces
This roadmap outlines the role semiconductor-based materials play in understanding the complex biophysical dynamics at multiple length …
Bozhi Tian
,
Shuai Xu
,
John A Rogers
,
Stefano Cestellos-Blanco
,
Peidong Yang
,
João L Carvalho-de-Souza
,
Francisco Bezanilla
,
Jia Liu
,
Zhenan Bao
,
Martin Hjort
,
Yuhong Cao
,
Nicholas Melosh
,
Guglielmo Lanzani
,
Fabio Benfenati
,
Giulia Galli
,
Francois Gygi
,
Rylan Kautz
,
Alon A Gorodetsky
,
Samuel S Kim
,
Timothy K Lu
,
Polina Anikeeva
,
Michal Cifra
,
Ondrej Krivosudsky
,
Daniel Havelka
,
Yuanwen Jiang
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DOI
Practical methods for generating alternating magnetic fields for biomedical research
Alternating magnetic fields (AMFs) cause magnetic nanoparticles (MNPs) to dissipate heat while leaving surrounding tissue unharmed, a …
Michael G Christiansen
,
Christina M Howe
,
David C Bono
,
David J Perreault
,
Polina Anikeeva
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DOI
Flexible and stretchable nanowire-coated fibers for optoelectronic probing of spinal cord circuits
Studies of neural pathways that contribute to loss and recovery of function following paralyzing spinal cord injury require devices for …
Chi Lu
,
Seongjun Park
,
Thomas J Richner
,
Alexander Derry
,
Imogen Brown
,
Chong Hou
,
Siyuan Rao
,
Jeewoo Kang
,
Chet T Moritz
,
Yoel Fink
,
Polina Anikeeva
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DOI
One-step optogenetics with multifunctional flexible polymer fibers
Optogenetic interrogation of neural pathways relies on delivery of light-sensitive opsins into tissue and subsequent optical …
Seongjun Park
,
Yuanyuan Guo
,
Xiaoting Jia
,
Han Kyoung Choe
,
Benjamin Grena
,
Jeewoo Kang
,
Jiyeon Park
,
Chi Lu
,
Andres Canales
,
Ritchie Chen
,
Yeong Shin Yim
,
Gloria B Choi
,
Yoel Fink
,
Polina Anikeeva
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DOI
Neural recording and modulation technologies
In the mammalian nervous system, billions of neurons connected by quadrillions of synapses exchange electrical, chemical and mechanical …
Ritchie Chen
,
Andres Canales
,
Polina Anikeeva
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DOI
Magnetically actuated protease sensors for in vivo tumor profiling
Targeted cancer therapies require a precise determination of the underlying biological processes driving tumorigenesis within the …
Simone Schuerle
,
Jaideep S Dudani
,
Michael G Christiansen
,
Polina Anikeeva
,
Sangeeta N Bhatia
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DOI
Magnetogenetics: Problems on the back of an envelope
Claims that magnetic fields can be used to manipulate biological systems contradict some basic laws of physics.
Polina Anikeeva
,
Alan Jasanoff
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DOI
Ion-switchable quantum dot Forster resonance energy transfer rates in ratiometric potassium sensors
The tools for optically imaging cellular potassium concentrations in real-time are currently limited to a small set of molecular …
Timothy T Ruckh
,
Christopher G Skipwith
,
Wendi Chang
,
Alexander W Senko
,
Vladimir Bulović
,
Polina Anikeeva
,
Heather A Clark
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DOI
Thermally drawn fibers as nerve guidance scaffolds
Synthetic neural scaffolds hold promise to eventually replace nerve autografts for tissue repair following peripheral nerve injury. …
Ryan A Koppes
,
Seongjun Park
,
Tiffany Hood
,
Xiaoting Jia
,
Negin Abdolrahim Poorheravi
,
Anilkumar Harapanahalli Achyuta
,
Yoel Fink
,
Polina Anikeeva
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DOI
High-performance ferrite nanoparticles through nonaqueous redox phase tuning
From magnetic resonance imaging to cancer hyperthermia and wireless control of cell signaling, ferrite nanoparticles produced by …
Ritchie Chen
,
Michael G Christiansen
,
Alexandra Sourakov
,
Alan Mohr
,
Yuri Matsumoto
,
Satoshi Okada
,
Alan Jasanoff
,
Polina Anikeeva
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DOI
Optogenetics unleashed
Since its introduction in 2005, optogenetics1 has become a go-to tool for deciphering neural pathways and identifying the contributions …
Polina Anikeeva
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DOI
Localized excitation of neural activity via rapid magnetothermal drug release
Hysteretic heat dissipation by magnetic nanoparticles (MNPs) in alternating magnetic fields (AMFs) allows these materials to act as …
Gabriela Romero
,
Michael G Christiansen
,
Ligia Stocche Barbosa
,
Francisco Garcia
,
Polina Anikeeva
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DOI
Engineering intracellular biomineralization and biosensing by a magnetic protein
Remote measurement and manipulation of biological systems can be achieved using magnetic techniques, but a missing link is the …
Yuri Matsumoto
,
Ritchie Chen
,
Polina Anikeeva
,
Alan Jasanoff
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DOI
Restoring the sense of touch
Amputation of damaged tissue is one of the oldest surgical techniques, reaching prevalence in the 16th century (1). Improved emergency …
Polina Anikeeva
,
Ryan A Koppes
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DOI
Remote-controlled mice
What if expression of a light-sensitive protein could be triggered wirelessly, on demand? What if optogenetics and neuropharmacology …
Polina Anikeeva
,
Xiaoting Jia
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DOI
Targeted Magnetic Nanoparticles for Remote Magnetothermal Disruption of Amyloid-β Aggregates
Remotely triggered hysteretic heat dissipation by magnetic nanoparticles (MNPs) selectively attached to targeted proteins can be used …
Colleen N Loynachan
,
Gabriela Romero
,
Michael G Christiansen
,
Ritchie Chen
,
Rachel Ellison
,
Tiernan T O'Malley
,
Ulrich P Froriep
,
Dominic M Walsh
,
Polina Anikeeva
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DOI
Optogenetic control of nerve growth
Due to the limited regenerative ability of neural tissue, a diverse set of biochemical and biophysical cues for increasing nerve growth …
Seongjun Park
,
Ryan A Koppes
,
Ulrich P Froriep
,
Xiaoting Jia
,
Anil Kumar H Achyuta
,
Bryan L McLaughlin
,
Polina Anikeeva
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DOI
Wireless magnetothermal deep brain stimulation
Wireless deep brain stimulation of well-defined neuronal populations could facilitate the study of intact brain circuits and the …
Ritchie Chen
,
Gabriela Romero
,
Michael G Christiansen
,
Alan Mohr
,
Polina Anikeeva
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DOI
Multifunctional fibers for simultaneous optical, electrical and chemical interrogation of neural circuits in vivo
Brain function depends on simultaneous electrical, chemical and mechanical signaling at the cellular level. This multiplicity has …
Andres Canales
,
Xiaoting Jia
,
Ulrich P Froriep
,
Ryan A Koppes
,
Christina Tringides
,
Jennifer Selvidge
,
Chi Lu
,
Chong Hou
,
Lei Wei
,
Yoel Fink
,
Polina Anikeeva
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DOI
Polymer fiber probes enable optical control of spinal cord and muscle function in vivo
Restoration of motor and sensory functions in paralyzed patients requires the development of tools for simultaneous recording and …
Chi Lu
,
Ulrich P Froriep
,
Ryan A Koppes
,
Andres Canales
,
Vittorio Caggiano
,
Jennifer Selvidge
,
Emilio Bizzi
,
Polina Anikeeva
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DOI
Natural neural projection dynamics underlying social behavior
Social interaction is a complex behavior essential for many species and is impaired in major neuropsychiatric disorders. …
Lisa A Gunaydin
,
Logan Grosenick
,
Joel C Finkelstein
,
Isaac V Kauvar
,
Lief E Fenno
,
Avishek Adhikari
,
Stephan Lammel
,
Julie J Mirzabekov
,
Raag D Airan
,
Kelly A Zalocusky
,
Kay M Tye
,
Polina Anikeeva
,
Robert C Malenka
,
Karl Delsseroth
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DOI
Bioelectronic medicines: a research roadmap
With the rapid rise in technology for the precision detection and modulation of electrical signalling patterns in the nervous system, a …
Karen Birmingham
,
Viviana Gradinaru
,
Polina Anikeeva
,
Warren M Grill
,
Victor Pikov
,
Bryan McLaughlin
,
Pankaj Pasricha
,
Douglas Weber
,
Kip Ludwig
,
Kristoffer Famm
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DOI
Magnetically multiplexed heating of single domain nanoparticles
Selective hysteretic heating of multiple collocated types of single domain magnetic nanoparticles (SDMNPs) by alternating magnetic …
Michael Christiansen
,
Alexander W Senko
,
Ritchie Chen
,
G Romero
,
Polina Anikeeva
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DOI
Optogenetic brain interfaces
The brain is a large network of interconnected neurons where each cell functions as a nonlinear processing element. Unraveling the …
Ramin Pashaie
,
Polina Anikeeva
,
Jin Hyung Lee
,
Rohit Prakash
,
Ofer Yizhar
,
Matthias Prigge
,
Divya Chander
,
Thomas J Richner
,
Justin Williams
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Optical control of neuronal excitation and inhibition using a single opsin protein, ChR2
The effect of electrical stimulation on neuronal membrane potential is frequency dependent. Low frequency electrical stimulation can …
Holly Liske
,
Xiang Qian
,
Polina Anikeeva
,
Karl Deisseroth
,
Scott Delp
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DOI
Maximizing hysteretic losses in magnetic ferrite nanoparticles via model-driven synthesis and materials optimization
This article develops a set of design guidelines for maximizing heat dissipation characteristics of magnetic ferrite MFe2O4 (M = Mn, …
Ritchie Chen
,
Michael G Christiansen
,
Polina Anikeeva
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DOI
Optical inhibition of motor nerve and muscle activity in vivo
Introduction: There is no therapeutic approach that provides precise and rapidly reversible inhibition of motor nerve and muscle …
Holly Liske
,
Chris Towne
,
Polina Anikeeva
,
Shengli Zhao
,
Guoping Feng
,
Karl Deisseroth
,
Scott Delp
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DOI
Photothermal genetic engineering
Optical methods for manipulation of cellular function have enabled deconstruction of genetic and neural circuits in vitro and in vivo. …
Polina Anikeeva
,
Karl Deisseroth
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DOI
Optetrode: a multichannel readout for optogenetic control in freely moving mice
Recent advances in optogenetics have improved the precision with which defined circuit elements can be controlled optically in freely …
Polina Anikeeva
,
Aaron S Andalman
,
Ilana Witten
,
Melissa Warden
,
Inbal Goshen
,
Logan Grosenick
,
Lisa A Gunaydin
,
Loren M Frank
,
Karl Deisseroth
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DOI
Morphology of contact printed colloidal quantum dots in organic semiconductor films: Implications for QD-LEDs
Quantum dot light emitting devices (QD‐LEDs) con‐sist of a monolayer of QDs sandwiched between a hole transporting layer (HTL) and …
Katherine E Aidala
,
Matthew J Panzer
,
Polina Anikeeva
,
Jonathan E Halpert
,
Moungi G Bawendi
,
Vladimir Bulović
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DOI
Cholinergic interneurons control local circuit activity and cocaine conditioning
Cholinergic neurons are widespread, and pharmacological modulation of acetylcholine receptors affects numerous brain processes, but …
Ilana B Witten
,
Shih-Chun Lin
,
Matthew Brodsky
,
Rohit Prakash
,
Ilka Diester
,
Polina Anikeeva
,
Viviana Gradinaru
,
Charu Ramakrishnan
,
Karl Deisseroth
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DOI
Nanoscale morphology revealed at the interface between colloidal quantum dots and organic semiconductor films
The degree of interpenetration at the interface between colloidal quantum dots (QDs) and organic semiconductor molecules commonly …
Matthew J Panzer
,
Katherine E Aidala
,
Polina Anikeeva
,
Jonathan E Halpert
,
Moungi G Bawendi
,
Vladimir Bulović
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DOI
Measuring charge trap occupation and energy level in CdSe/ZnS quantum dots using a scanning tunneling microscope
We use a scanning tunneling microscope to probe single-electron charging phenomena in individual CdSe/ZnS (core/shell) quantum dots …
MR Hummon
,
AJ Stollenwerk
,
V Narayanamurti
,
Polina Anikeeva
,
MJ Panzer
,
V Wood
,
V Bulović
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DOI
Efficient Förster energy transfer from phosphorescent organic molecules to J-aggregate thin films
We demonstrate efficient Förster resonance energy transfer (FRET) from a thin film of phosphorescent dye, fac tris(2-phenylpyridine) …
Yasuhiro Shirasaki
,
Polina Anikeeva
,
Jonathan R Tischler
,
M Scott Bradley
,
Vladimir Bulović
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DOI
Quantum dot light-emitting devices with electroluminescence tunable over the entire visible spectrum
Improvements in quantum dot light-emitting device (QD-LED) performance are achieved by the choice of organic charge transporting …
Polina Anikeeva
,
Jonathan E Halpert
,
Moungi G Bawendi
,
Vladimir Bulović
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DOI
Contact printing of quantum dot light-emitting devices
We demonstrate a solvent-free contact printing process for deposition of patterned and unpatterned colloidal quantum dot (QD) thin …
LeeAnn Kim
,
Polina Anikeeva
,
Seth A Coe-Sullivan
,
Jonathan S Steckel
,
Moungi G Bawendi
,
Vladimir Bulović
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DOI
Electronic and excitonic processes in light-emitting devices based on organic materials and colloidal quantum dots
We investigate the mechanism of operation of hybrid organic/colloidal quantum dot light emitting devices (QD-LEDs). Novel quantum dot …
Polina Anikeeva
,
CF Madigan
,
Jonathan Eugene Halpert
,
MG Bawendi
,
V Bulović
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Electroluminescence from a mixed red- green- blue colloidal quantum dot monolayer
We demonstrate light emitting devices (LEDs) with a broad spectral emission generated by electroluminescence from a mixed-monolayer of …
Polina Anikeeva
,
Jonathan E Halpert
,
Moungi G Bawendi
,
Vladimir Bulović
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DOI
Color-saturated green-emitting QD-LEDs
Green to the core : Cdx Zn1−x Se alloy core nanocrystals are synthesized and overcoated with Cdy Zn1−y S to create core–shell …
Jonathan S Steckel
,
Preston Snee
,
Seth Coe-Sullivan
,
John P Zimmer
,
Jonathan E Halpert
,
Polina Anikeeva
,
Lee-Ann Kim
,
Vladimir Bulović
,
Moungi G Bawendi
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DOI
Photoluminescence of CdSe/ZnS core/shell quantum dots enhanced by energy transfer from a phosphorescent donor
We demonstrate exciton energy transfer from a thin film of phosphorescent dye fac tris(2-phenylpyridine) iridium (Ir(ppy)3) to a …
Polina Anikeeva
,
CF Madigan
,
SA Coe-Sullivan
,
JS Steckel
,
MG Bawendi
,
V Bulović
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DOI
Light amplification using inverted core/shell nanocrystals: towards lasing in the single-exciton regime
Size-controlled spectral tunability and chemical flexibility make semiconductor nanocrystals (NCs) attractive as nanoscale building …
Sergei A Ivanov
,
Jagjit Nanda
,
Andrei Piryatinski
,
Marc Achermann
,
Laurent P Balet
,
Ilia V Bezel
,
Polina Anikeeva
,
Sergei Tretiak
,
Victor I Klimov
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